I would recommend using a good estate planning and probate attorney. If you have a relatively low amount of assets you can get by with a Will, a Durable Power of Attorney, Living Will, and the related medical issues doc's - DNR orders etc... [If you have a large amount of assets and a large family you may want to go the Trust route].
As part of the process have all your financial accounts (bank accounts, IRA's, Trusts, investment/brokerage accounts) be titled, or include, with TOD designations (Transfer on Death, to a named beneficiary(s)) so that most or all of your assets can transfer directly to your designees without having to go through probate, which is costly and time consuming. This would include changing the deed to your home to also be TOD. This way, your assets transfer directly as specified, without probate, and then your Will basically just becomes a 'catch-all' to transfer anything that you missed with a TOD designation. If structured properly with the help of a good estate attorney and your own titling of your accounts, then little to nothing would have to go through probate.
And at some point, let those who will be responsible for handling your affairs know where everything is and how you have things structured.