Clearwater to St. Petersburg; Siesta Key; Naples; Marco Island; Marathon (especially if you like salt-water fishing) .................
I have been to Florida several times, but at least 3 of them were to the Orlando area, and the only other time I can remember is going to Jacksonville for the Gator Bowl in 2010.
I've always wanted to go to Pensacola for a Blue Wahoos minor league game. What other places are worth visiting? We should be able to go down for a week in April but haven't decided on a location. My wife found Port St Joe and it looks nice. It's also close to Panama City.