queencitybuckeye;1437596 wrote:I'm assuming you're talking about recreational use (we disagree but so what). I'm still waiting for a rational explanation why a child who has life-threatening seizures can't legally have a treatment known to be effective.
Glory Days;1437705 wrote:got a scientific study to prove it? some parent giving pot to their kid and saying it works isnt scientific.
GOONx19;1438627 wrote:

Glory Days;1438689 wrote:I dont know much about Nabiximal but from what i have read it works about 50% of the time, isnt exactly marijuana and isnt supposed to get you high.
Nabiximols works the same way as marijuana. It stimulates cannabinoid receptors CB1 and CB2 in the central nervous system and dorsal root ganglia as well as other site of the body. Peripheral CB2 receptors modulate immune function through cytokine release. Your initial post wasn't about getting a patient high, it was about whether or not it could reduce seizures. Stimulating these receptors does reduce seizures. You asked for a scientific study that proves this. I gave you one. This is a randomized, peer-reviewed, double-blind, controlled study. It's as high a level of evidence as you can get in medical literature. If you read it, instead of whatever else you've been reading, you'll see that is doesn't work only 50% of the time. There is a 98.8% reduction is spasm frequency when these receptors are stimulated, with a p-value of 0.005. This means that 99.5% of the time you will see this reduction in spasm frequency. The patient and the patient's caregivers should have the option to utilize this therapy if they so choose. Getting high is a potential side effect of more than just smoking weed.