But I never, ever let anyone else make my airline reservations. I can usually beat their price, or I juggle priorities based on what I find out there. I might be willing to a spend a bit more to avoid changing planes in Chicago in the winter or a too-tight connection in Phoenix during monsoon season - or a lot more to make sure a "last flight of the day" connection is at an airport close enough to drive the rest of the way if things go wrong. Seating makes a difference,too - I can endure a middle seat from Columbus to Detroit, but not from Detroit to the West Coast.
The last time I let our corporate travel agent do it for me, I was booked home from Portland to Salt Lake City to Detroit to Columbus - with a 35 minute connection in Utah, a middle seat on Detroit flight and a three-hour wait in Michigan.